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KLONOPIN is an anti-anxiety medication in the benzodiazepine family, the same family that includes diazepam (Valium), alprazolam (Xanax), lorazepam (Ativan), flurazepam (Dalmane), and others. Clonazepam and other benzodiazepines act by enhancing the effects of gamma-aminobutyric acid (GABA) in the brain. GABA is a neurotransmitter (a chemical that nerve cells use to communicate with each other) that inhibits brain activity. It is believed that excessive activity in the brain may lead to anxiety or other psychiatric disorders. Clonazepam is primarily used for treating panic disorder and preventing certain types of seizures.

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Increased risk of drug-related mortality from concomitant use with opioids. Suicidal thoughts or behavior (monitor). Depression. May increase or precipitate tonic-clonic seizures. Compromised respiratory function (eg, COPD, sleep apnea). Porphyria. Monitor LFTs, CBCs during long-term therapy. Assess patient's risk for abuse, misuse, addiction prior to and during therapy. Avoid abrupt cessation. Withdraw gradually. Drug or alcohol abusers. Renal impairment. Elderly. Labor & delivery. Pregnancy. Nursing mothers.

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Klonopin / Clonazepam should be taken according to the doctor's prescription. It is up to your doctor to determine the dose of Klonopin / Clonazepam indicated for you and the duration of therapy. Do not change the prescribed dosage on your own initiative. If you think that the action of the medicine is too weak or too strong, talk to your doctor or pharmacist. To avoid side effects at the start of therapy, the doctor will gradually increase the daily dose until the required maintenance dose is reached. Generally the dosage for adults is as follows: starting dose: 1.5 mg / day (one light orange 0.5 mg tablet 3 times a day). Within the first three weeks of treatment, your doctor will increase the dose to 4-8 mg / day (in rare cases up to 20 mg / day). The total daily dose can be taken in a single dose in the evening. However, the doctor may consider it appropriate to divide the daily dose into several administrations during the day. In elderly patients, the physician should prescribe the lowest possible dose and dose escalation should be done with caution. To facilitate dosage adjustment, Klonopin / Clonazepam 0.5 mg tablets can be halved. Klonopin / Clonazepam 2 mg tablets can be halved or divided into four parts to facilitate dosage adjustment.
Klonopin / Clonazepam treatment should never be stopped abruptly. With regard to epileptic children and infants, the doctor will in any case decide whether Klonopin / Clonazepam therapy is suitable. For children and infants, 0.5 mg light orange tablets or drops are indicated. Take Klonopin / Clonazepam tablets with a glass of water or a non-alcoholic drink. Never drip Klonopin / Clonazepam drops directly into the mouth. After each opening of the bottle, make sure that the dropper is firmly inserted into the neck of the bottle. The drops are administered with a spoon, mixed with water, tea or orange juice.

How long does Klonopin last?
Klonopin starts working fairly quickly. You can start feeling its effects within an hour. Klonopin usually lasts for 8-12 hours, meaning you should be able to sleep through the night when you are on the right dose for you of this medication. The right dose is essential, otherwise a person will wake up in the middle of the night if the dose is too low or sleep late into the morning if the dose is too high.


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